diff --git a/src/main/services/SelectionService.ts b/src/main/services/SelectionService.ts
index 16aaac6890..49ed189055 100644
--- a/src/main/services/SelectionService.ts
+++ b/src/main/services/SelectionService.ts
@@ -14,6 +14,7 @@ import type {
 
 import type { ActionItem } from '../../renderer/src/types/selectionTypes'
 import { ConfigKeys, configManager } from './ConfigManager'
+import storeSyncService from './StoreSyncService'
 
 let SelectionHook: SelectionHookConstructor | null = null
 try {
@@ -334,6 +335,20 @@ export class SelectionService {
     this.logInfo('SelectionService Quitted')
   }
 
+  /**
+   * Toggle the enabled state of the selection service
+   * Will sync the new enabled store to all renderer windows
+   */
+  public toggleEnabled(enabled: boolean | undefined = undefined) {
+    if (!this.selectionHook) return
+
+    const newEnabled = enabled === undefined ? !configManager.getSelectionAssistantEnabled() : enabled
+
+    configManager.setSelectionAssistantEnabled(newEnabled)
+
+    //sync the new enabled state to all renderer windows
+    storeSyncService.syncToRenderer('selectionStore/setSelectionEnabled', newEnabled)
+  }
   /**
    * Create and configure the toolbar window
    * Sets up window properties, event handlers, and loads the toolbar UI
diff --git a/src/main/services/ShortcutService.ts b/src/main/services/ShortcutService.ts
index d69c80b325..0bf696d4bf 100644
--- a/src/main/services/ShortcutService.ts
+++ b/src/main/services/ShortcutService.ts
@@ -4,10 +4,15 @@ import { BrowserWindow, globalShortcut } from 'electron'
 import Logger from 'electron-log'
 
 import { configManager } from './ConfigManager'
+import selectionService from './SelectionService'
 import { windowService } from './WindowService'
 
 let showAppAccelerator: string | null = null
 let showMiniWindowAccelerator: string | null = null
+let selectionAssistantToggleAccelerator: string | null = null
+
+//indicate if the shortcuts are registered on app boot time
+let isRegisterOnBoot = true
 
 // store the focus and blur handlers for each window to unregister them later
 const windowOnHandlers = new Map<BrowserWindow, { onFocusHandler: () => void; onBlurHandler: () => void }>()
@@ -28,6 +33,12 @@ function getShortcutHandler(shortcut: Shortcut) {
       return () => {
         windowService.toggleMiniWindow()
       }
+    case 'selection_assistant_toggle':
+      return () => {
+        if (selectionService) {
+          selectionService.toggleEnabled()
+        }
+      }
     default:
       return null
   }
@@ -93,11 +104,14 @@ const convertShortcutRecordedByKeyboardEventKeyValueToElectronGlobalShortcutForm
 }
 
 export function registerShortcuts(window: BrowserWindow) {
-  window.once('ready-to-show', () => {
-    if (configManager.getLaunchToTray()) {
-      registerOnlyUniversalShortcuts()
-    }
-  })
+  if (isRegisterOnBoot) {
+    window.once('ready-to-show', () => {
+      if (configManager.getLaunchToTray()) {
+        registerOnlyUniversalShortcuts()
+      }
+    })
+    isRegisterOnBoot = false
+  }
 
   //only for clearer code
   const registerOnlyUniversalShortcuts = () => {
@@ -124,7 +138,10 @@ export function registerShortcuts(window: BrowserWindow) {
         }
 
         // only register universal shortcuts when needed
-        if (onlyUniversalShortcuts && !['show_app', 'mini_window'].includes(shortcut.key)) {
+        if (
+          onlyUniversalShortcuts &&
+          !['show_app', 'mini_window', 'selection_assistant_toggle'].includes(shortcut.key)
+        ) {
           return
         }
 
@@ -146,6 +163,10 @@ export function registerShortcuts(window: BrowserWindow) {
             showMiniWindowAccelerator = formatShortcutKey(shortcut.shortcut)
             break
 
+          case 'selection_assistant_toggle':
+            selectionAssistantToggleAccelerator = formatShortcutKey(shortcut.shortcut)
+            break
+
           //the following ZOOMs will register shortcuts seperately, so will return
           case 'zoom_in':
             globalShortcut.register('CommandOrControl+=', () => handler(window))
@@ -192,6 +213,14 @@ export function registerShortcuts(window: BrowserWindow) {
           convertShortcutRecordedByKeyboardEventKeyValueToElectronGlobalShortcutFormat(showMiniWindowAccelerator)
         handler && globalShortcut.register(accelerator, () => handler(window))
       }
+
+      if (selectionAssistantToggleAccelerator) {
+        const handler = getShortcutHandler({ key: 'selection_assistant_toggle' } as Shortcut)
+        const accelerator = convertShortcutRecordedByKeyboardEventKeyValueToElectronGlobalShortcutFormat(
+          selectionAssistantToggleAccelerator
+        )
+        handler && globalShortcut.register(accelerator, () => handler(window))
+      }
     } catch (error) {
       Logger.error('[ShortcutService] Failed to unregister shortcuts')
     }
@@ -217,6 +246,7 @@ export function unregisterAllShortcuts() {
   try {
     showAppAccelerator = null
     showMiniWindowAccelerator = null
+    selectionAssistantToggleAccelerator = null
     windowOnHandlers.forEach((handlers, window) => {
       window.off('focus', handlers.onFocusHandler)
       window.off('blur', handlers.onBlurHandler)
diff --git a/src/main/services/StoreSyncService.ts b/src/main/services/StoreSyncService.ts
index 84d84d1ad4..57f07195b6 100644
--- a/src/main/services/StoreSyncService.ts
+++ b/src/main/services/StoreSyncService.ts
@@ -49,6 +49,23 @@ export class StoreSyncService {
     this.windowIds = this.windowIds.filter((id) => id !== windowId)
   }
 
+  /**
+   * Sync an action to all renderer windows
+   * @param type Action type, like 'settings/setTray'
+   * @param payload Action payload
+   *
+   * NOTICE: DO NOT use directly in ConfigManager, may cause infinite sync loop
+   */
+  public syncToRenderer(type: string, payload: any): void {
+    const action: StoreSyncAction = {
+      type,
+      payload
+    }
+
+    //-1 means the action is from the main process, will be broadcast to all windows
+    this.broadcastToOtherWindows(-1, action)
+  }
+
   /**
    * Register IPC handlers for store sync communication
    * Handles window subscription, unsubscription and action broadcasting
diff --git a/src/renderer/src/i18n/locales/en-us.json b/src/renderer/src/i18n/locales/en-us.json
index fc20b5ab7d..9a8d70a3ea 100644
--- a/src/renderer/src/i18n/locales/en-us.json
+++ b/src/renderer/src/i18n/locales/en-us.json
@@ -1701,6 +1701,7 @@
         "exit_fullscreen": "Exit Fullscreen",
         "key": "Key",
         "mini_window": "Quick Assistant",
+        "selection_assistant_toggle": "Toggle Selection Assistant",
         "new_topic": "New Topic",
         "press_shortcut": "Press Shortcut",
         "reset_defaults": "Reset Defaults",
diff --git a/src/renderer/src/i18n/locales/ja-jp.json b/src/renderer/src/i18n/locales/ja-jp.json
index 576205e028..108bc5b49f 100644
--- a/src/renderer/src/i18n/locales/ja-jp.json
+++ b/src/renderer/src/i18n/locales/ja-jp.json
@@ -1689,6 +1689,7 @@
         "exit_fullscreen": "フルスクリーンを終了",
         "key": "キー",
         "mini_window": "クイックアシスタント",
+        "selection_assistant_toggle": "選択アシスタントを切り替え",
         "new_topic": "新しいトピック",
         "press_shortcut": "ショートカットを押す",
         "reset_defaults": "デフォルトのショートカットをリセット",
diff --git a/src/renderer/src/i18n/locales/ru-ru.json b/src/renderer/src/i18n/locales/ru-ru.json
index 024718b008..e469c89592 100644
--- a/src/renderer/src/i18n/locales/ru-ru.json
+++ b/src/renderer/src/i18n/locales/ru-ru.json
@@ -1689,6 +1689,7 @@
         "exit_fullscreen": "Выйти из полноэкранного режима",
         "key": "Клавиша",
         "mini_window": "Быстрый помощник",
+        "selection_assistant_toggle": "Переключить помощник выделения",
         "new_topic": "Новый топик",
         "press_shortcut": "Нажмите сочетание клавиш",
         "reset_defaults": "Сбросить настройки по умолчанию",
diff --git a/src/renderer/src/i18n/locales/zh-cn.json b/src/renderer/src/i18n/locales/zh-cn.json
index 4edad4311c..548089e76e 100644
--- a/src/renderer/src/i18n/locales/zh-cn.json
+++ b/src/renderer/src/i18n/locales/zh-cn.json
@@ -1701,6 +1701,7 @@
         "exit_fullscreen": "退出全屏",
         "key": "按键",
         "mini_window": "快捷助手",
+        "selection_assistant_toggle": "开关划词助手",
         "new_topic": "新建话题",
         "press_shortcut": "按下快捷键",
         "reset_defaults": "重置默认快捷键",
diff --git a/src/renderer/src/i18n/locales/zh-tw.json b/src/renderer/src/i18n/locales/zh-tw.json
index ac7334089b..080cef0fad 100644
--- a/src/renderer/src/i18n/locales/zh-tw.json
+++ b/src/renderer/src/i18n/locales/zh-tw.json
@@ -1691,6 +1691,7 @@
         "copy_last_message": "複製上一則訊息",
         "key": "按鍵",
         "mini_window": "快捷助手",
+        "selection_assistant_toggle": "開關劃詞助手",
         "new_topic": "新增話題",
         "press_shortcut": "按下快捷鍵",
         "reset_defaults": "重設預設快捷鍵",
diff --git a/src/renderer/src/pages/settings/ShortcutSettings.tsx b/src/renderer/src/pages/settings/ShortcutSettings.tsx
index d392fee3eb..4d4cb3321f 100644
--- a/src/renderer/src/pages/settings/ShortcutSettings.tsx
+++ b/src/renderer/src/pages/settings/ShortcutSettings.tsx
@@ -18,10 +18,17 @@ const ShortcutSettings: FC = () => {
   const { t } = useTranslation()
   const { theme } = useTheme()
   const dispatch = useAppDispatch()
-  const { shortcuts } = useShortcuts()
+  const { shortcuts: originalShortcuts } = useShortcuts()
   const inputRefs = useRef<Record<string, InputRef>>({})
   const [editingKey, setEditingKey] = useState<string | null>(null)
 
+  //TODO: if shortcut is not available on all the platforms, block the shortcut here
+  let shortcuts = originalShortcuts
+  if (!isWindows) {
+    //Selection Assistant only available on Windows now
+    shortcuts = shortcuts.filter((s) => s.key !== 'selection_assistant_toggle')
+  }
+
   const handleClear = (record: Shortcut) => {
     dispatch(
       updateShortcut({
diff --git a/src/renderer/src/store/migrate.ts b/src/renderer/src/store/migrate.ts
index f792383afd..9086a03b98 100644
--- a/src/renderer/src/store/migrate.ts
+++ b/src/renderer/src/store/migrate.ts
@@ -1508,6 +1508,24 @@ const migrateConfig = {
         state.llm.translateModel = SYSTEM_MODELS.defaultModel[2]
       }
 
+      // Add selection_assistant_toggle shortcut after mini_window if it doesn't exist
+      if (state.shortcuts) {
+        const miniWindowIndex = state.shortcuts.shortcuts.findIndex((shortcut) => shortcut.key === 'mini_window')
+        const hasSelectionAssistant = state.shortcuts.shortcuts.some(
+          (shortcut) => shortcut.key === 'selection_assistant_toggle'
+        )
+
+        if (miniWindowIndex !== -1 && !hasSelectionAssistant) {
+          state.shortcuts.shortcuts.splice(miniWindowIndex + 1, 0, {
+            key: 'selection_assistant_toggle',
+            shortcut: [],
+            editable: true,
+            enabled: false,
+            system: true
+          })
+        }
+      }
+
       return state
     } catch (error) {
       return state
diff --git a/src/renderer/src/store/shortcuts.ts b/src/renderer/src/store/shortcuts.ts
index 93080f4f3d..c0c110f5a4 100644
--- a/src/renderer/src/store/shortcuts.ts
+++ b/src/renderer/src/store/shortcuts.ts
@@ -31,6 +31,14 @@ const initialState: ShortcutsState = {
       enabled: false,
       system: true
     },
+    {
+      //enable/disable selection assistant
+      key: 'selection_assistant_toggle',
+      shortcut: [],
+      editable: true,
+      enabled: false,
+      system: true
+    },
     {
       key: 'new_topic',
       shortcut: [isMac ? 'Command' : 'Ctrl', 'N'],
@@ -45,6 +53,7 @@ const initialState: ShortcutsState = {
       enabled: true,
       system: false
     },
+
     {
       key: 'toggle_show_topics',
       shortcut: [isMac ? 'Command' : 'Ctrl', ']'],